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KMID : 1134820160450101414
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Journal of the Korean Society of Food Science and Nutrition
2016 Volume.45 No. 10 p.1414 ~ p.1421
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Comparison of Linarin Content and Biological Activity in Ethanol Extraction of Chrysanthemum zawadskii
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Kim Yang-Ji
Kim Seong-Eun
Lee Hak-Sung
Hong Su-Young
Kim Young-Jun
Lee Jin-Hyup
Park Sung-Jin
Kim Jun-Ho
Park Youn-Je
Kim Hyun-Kyu
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Abstract
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This study was designed to determine optimal extraction conditions of Chrysanthemum zawadskii (CZ) with high yield of bioactive compounds (linarin, polyphenols, and flavonoids) and improved in vitro activities. Ethanol extracts were examined at different concentrations (0, 30, 50, 70, and 95%) and temperatures (50 and 70°C). The recommended extraction conditions were 50% ethanol at 70°C for 4 h, which gave the highest yield of linarin, polyphenols, and flavonoids. This extract appeared to have the greatest ABTS and DPPH radical scavenging activities (87.81% and 51.42% at 500 μg/mL, respectively) and α-glucosidase (74.59%) and pancreatic lipase inhibitory activities (90.44%). As contents of linarin increased, antioxidative activity, inhibitory effects of carbohydrates and lipid absorption of CZ extracts increased as well. From these results, CZ extracts can be used in functional food industries.
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KEYWORD
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Chrysanthemum zawadskii, linarin, a-glucosidase, lipase, antioxidant
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